If you haven't and you do Microsoft development, give an ear to John Galloway, K. Scott Allen, Scott Koon, and Keven Dente in their "Technology Roundtable" podcast. There are a lot of podcasts I find entertaining, (like Joel and Jeff's discussions) but these guys seem to do what I do - and to contextualize that since it may sound presumptuous, they deal with Microsoft development tools building "real world" software.
I try to have "take aways" from podcasts so from the first more impetus to investigate Ninject and dependency injection as well as more investigation of LINQ to SQL and the ADO.NET Entity framework (opinions flew on these, I'd like to develop some of my own). Finally, even though I'll probably skip the beta, I will look forward to .NET 3.5 SP1 since ASP.NET Dynamic Data will be packaged therein.
I'll stay tuned, it will be interesting to see what they talk about next time.